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Methylation associated transcriptional repression of ELOVL5 in novel colorectal cancer cell lines
Genetic and epigenetic alterations mark colorectal cancer (CRC). Global hypomethylation is observed in nearly all CRC, but a distinct subset of CRC show the CpG Island Methylator Phenotype (CIMP). These tumors show DNA hypermethylation of a specific subset of CpG islands, resulting in transcriptiona...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5607170/ https://ncbi.nlm.nih.gov/pubmed/28931069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184900 |
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