BRAF mutation-specific promoter methylation of FOX genes in colorectal cancer

BACKGROUND: Cancer-specific hypermethylation of (promoter) CpG islands is common during the tumorigenesis of colon cancer. Although associations between certain genetic aberrations, such as BRAF mutation and microsatellite instability, and the CpG island methylator phenotype (CIMP), have been found,...

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Bibliografiske detaljer
Main Authors: van Roon, Eddy H, Boot, Arnoud, Dihal, Ashwin A, Ernst, Robert F, van Wezel, Tom, Morreau, Hans, Boer, Judith M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3599401/
https://ncbi.nlm.nih.gov/pubmed/23324568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-5-2
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