Allelic Switching of DLX5, GRB10, and SVOPL during Colorectal Cancer Tumorigenesis

Allele-specific expression (ASE) is found in approximately 20-30% of human genes. During tumorigenesis, ASE changes due to somatic alterations that change the regulatory landscape. In colorectal cancer (CRC), many chromosomes show frequent gains or losses while homozygosity of chromosome 7 is rare....

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Detalhes bibliográficos
Publicado no:Int J Genomics
Main Authors: Boot, Arnoud, Oosting, Jan, Doorn, Saskia, Ouahoud, Sarah, Ventayol Garcia, Marina, Ruano, Dina, Morreau, Hans, van Wezel, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6481143/
https://ncbi.nlm.nih.gov/pubmed/31093489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1287671
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