Tumour-specific methylation of PTPRG intron 1 locus in sporadic and Lynch syndrome colorectal cancer

DNA methylation is a hallmark in a subset of right-sided colorectal cancers. Methylation-based screening may improve prevention and survival rate for this type of cancer, which is often clinically asymptomatic in the early stages. We aimed to discover prognostic or diagnostic biomarkers for colon ca...

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Main Authors: van Roon, Eddy H J, de Miranda, Noël F C C, van Nieuwenhuizen, Merlijn P, de Meijer, Emile J, van Puijenbroek, Marjo, Yan, Pearlly S, Huang, Tim H-M, van Wezel, Tom, Morreau, Hans, Boer, Judith M
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061992/
https://ncbi.nlm.nih.gov/pubmed/21150880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.187
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