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Tumor LINE-1 Methylation Level in Association with Survival of Patients with Stage II Colon Cancer

Genome-wide DNA hypomethylation is associated with a worse prognosis in early-stage colorectal cancer. To measure genome-wide DNA methylation levels, long interspersed nucleotide element (LINE-1) repeats are used as a surrogate marker. Cohort studies on the clinical impact of genome-wide DNA methyla...

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Main Authors: Marloes Swets, Anniek Zaalberg, Arnoud Boot, Tom van Wezel, Martine A. Frouws, Esther Bastiaannet, Hans Gelderblom, Cornelis J. H. van de Velde, Peter J. K. Kuppen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2016-12-01
Colecção:International Journal of Molecular Sciences
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Acesso em linha:http://www.mdpi.com/1422-0067/18/1/36
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