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Hypoxia Regulates Choline Kinase Expression through Hypoxia-Inducible Factor-1α Signaling in a Human Prostate Cancer Model

The intensity of the total choline (tCho) signal in spectroscopic images of tumors is spatially heterogeneous. The likewise heterogeneous physiologic tumor microenvironment may contribute to this heterogeneity. We therefore investigated the relationship between hypoxia, choline metabolites, and chol...

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Publicat a:Cancer Res
Autors principals: Glunde, Kristine, Shah, Tariq, Winnard, Paul T., Raman, Venu, Takagi, Tomoyo, Vesuna, Farhad, Artemov, Dmitri, Bhujwalla, Zaver M.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606139/
https://ncbi.nlm.nih.gov/pubmed/18172309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-2678
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