Hypoxia Regulates Choline Kinase Expression through Hypoxia-Inducible Factor-1α Signaling in a Human Prostate Cancer Model

The intensity of the total choline (tCho) signal in spectroscopic images of tumors is spatially heterogeneous. The likewise heterogeneous physiologic tumor microenvironment may contribute to this heterogeneity. We therefore investigated the relationship between hypoxia, choline metabolites, and chol...

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Vydáno v:Cancer Res
Hlavní autoři: Glunde, Kristine, Shah, Tariq, Winnard, Paul T., Raman, Venu, Takagi, Tomoyo, Vesuna, Farhad, Artemov, Dmitri, Bhujwalla, Zaver M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606139/
https://ncbi.nlm.nih.gov/pubmed/18172309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-2678
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