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Noninvasive Detection of Lentiviral-Mediated Choline Kinase Targeting In a Human Breast Cancer Xenograft

Elevated phosphocholine (PC) and total choline metabolites are widely established characteristics of most cancer cells including breast cancer. Effective silencing of choline kinase (chk), the enzyme that converts choline to phosphocholine, is associated with reduced tumor growth. The functional imp...

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Detalhes bibliográficos
Main Authors: Balaji, Krishnamachary, Glunde, Kristine, Wildes, Flonne, Mori, Noriko, Takagi, Tomoyo, Raman, Venu, Bhujwalla, Zaver M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687146/
https://ncbi.nlm.nih.gov/pubmed/19336572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4120
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