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Choline kinase overexpression increases invasiveness and drug resistance of human breast cancer cells

A direct correlation exists between increased choline kinase (Chk) expression, the resulting increase of phosphocholine levels, and histological tumor grade. To better understand the function of Chk and choline phospholipid metabolism in breast cancer we have stably overexpressed one of the two isof...

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Detalhes bibliográficos
Main Authors: Shah, Tariq, Wildes, Flonne, Penet, Marie-France, Winnard, Paul T., Glunde, Kristine, Artemov, Dmitri, Ackerstaff, Ellen, Gimi, Barjor, Kakkad, Samata, Raman, Venu, Bhujwalla, Zaver M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115627/
https://ncbi.nlm.nih.gov/pubmed/20623626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.1510
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