Choline kinase overexpression increases invasiveness and drug resistance of human breast cancer cells

A direct correlation exists between increased choline kinase (Chk) expression, the resulting increase of phosphocholine levels, and histological tumor grade. To better understand the function of Chk and choline phospholipid metabolism in breast cancer we have stably overexpressed one of the two isof...

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Bibliographic Details
Main Authors: Shah, Tariq, Wildes, Flonne, Penet, Marie-France, Winnard, Paul T., Glunde, Kristine, Artemov, Dmitri, Ackerstaff, Ellen, Gimi, Barjor, Kakkad, Samata, Raman, Venu, Bhujwalla, Zaver M.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115627/
https://ncbi.nlm.nih.gov/pubmed/20623626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.1510
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