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A FOXO1-induced oncogenic network defines the AML1-ETO preleukemic program
Understanding and blocking the self-renewal pathway of preleukemia stem cells could prevent acute myeloid leukemia (AML) relapse. In this study, we show that increased FOXO1 represents a critical mechanism driving aberrant self-renewal in preleukemic cells expressing the t(8;21)-associated oncogene...
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| I publikationen: | Blood |
|---|---|
| Huvudupphovsmän: | , , , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society of Hematology
2017
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5606002/ https://ncbi.nlm.nih.gov/pubmed/28710059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-11-750976 |
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