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C/EBPα overrides epigenetic reprogramming by oncogenic transcription factors in acute myeloid leukemia
Acute myeloid leukemia (AML) is a heterogeneous disease caused by recurrent mutations in the transcription regulatory machinery, resulting in abnormal growth and a block in differentiation. One type of recurrent mutations affects RUNX1, which is subject to mutations and translocations, the latter gi...
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| Publicado no: | Blood Adv |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5812331/ https://ncbi.nlm.nih.gov/pubmed/29431622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017012781 |
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