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A comprehensive characterization of PncA polymorphisms that confer resistance to pyrazinamide
Tuberculosis chemotherapy is dependent on the use of the antibiotic pyrazinamide, which is being threatened by emerging drug resistance. Resistance is mediated through mutations in the bacterial gene pncA. Methods for testing pyrazinamide susceptibility are difficult and rarely performed, and this m...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5605632/ https://ncbi.nlm.nih.gov/pubmed/28928454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00721-2 |
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