Rapid Sequencing of the Mycobacterium tuberculosis pncA Gene for Detection of Pyrazinamide Susceptibility

We developed a pyrazinamidase gene DNA-sequencing method to rapidly identify pyrazinamide resistance-causing mutations in GenoLyse-treated, smear-positive sputum specimens. The sensitivity and specificity were 90.9 and 100%, respectively, compared to those of MGIT drug susceptibility testing, after...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Microbiol
Prif Awduron: Streicher, Elizabeth M., Maharaj, Kashmeel, York, Talita, Van Heerden, Carel, Barnard, Marinus, Diacon, Andreas, Mendel, Carl M., Bosman, Marlein E., Hepple, Juli A., Pym, Alexander S., Warren, Robin M., van Helden, Paul D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2014
Pynciau:
Mycobacteriology and Aerobic Actinomycetes
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313251/
https://ncbi.nlm.nih.gov/pubmed/25165081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02438-14
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