Direct Detection of Pyrazinamide Resistance in Mycobacterium tuberculosis by Use of pncA PCR Sequencing

An in-house-developed pncA sequencing assay for analysis of pyrazinamide (PZA) resistance was evaluated using 162 archived Mycobacterium tuberculosis complex (MTBC) isolates with phenotypic PZA susceptibility profiles that were well defined by analysis of Bactec MGIT 960 PZA kit and PZase activity d...

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Main Authors: Tam, Kingsley King-Gee, Leung, Kenneth Siu-Sing, Siu, Gilman Kit-Hang, Chang, Kwok-Chiu, Wong, Samson Sai-Yin, Ho, Pak-Leung, Leung, Eunice Ka-Chun, Yam, Wing-Cheong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Mycobacteriology and Aerobic Actinomycetes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6663915/
https://ncbi.nlm.nih.gov/pubmed/31189582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00145-19
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