Pyrazinamide resistance-conferring mutations in pncA and the transmission of multidrug resistant TB in Georgia

BACKGROUND: The ongoing epidemic of multidrug-resistant tuberculosis (MDR-TB) in Georgia highlights the need for more effective control strategies. A new regimen to treat MDR-TB that includes pyrazinamide (PZA) is currently being evaluated and PZA resistance status will largely influence the success...

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Detalhes bibliográficos
Publicado no:BMC Infect Dis
Main Authors: Sengstake, Sarah, Bergval, Indra L, Schuitema, Anja R, de Beer, Jessica L, Phelan, Jody, de Zwaan, Rina, Clark, Taane G, van Soolingen, Dick, Anthony, Richard M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506614/
https://ncbi.nlm.nih.gov/pubmed/28697808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-017-2594-3
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