Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer

The presence of tumor-infiltrating lymphocytes in triple-negative breast cancers is correlated with improved outcomes. Ras/MAPK pathway activation is associated with significantly lower levels of tumor-infiltrating lymphocytes in triple-negative breast cancers and while MEK inhibition can promote re...

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保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Dushyanthen, Sathana, Teo, Zhi Ling, Caramia, Franco, Savas, Peter, Mintoff, Christopher P., Virassamy, Balaji, Henderson, Melissa A., Luen, Stephen J., Mansour, Mariam, Kershaw, Michael H., Trapani, Joseph A., Neeson, Paul J., Salgado, Roberto, McArthur, Grant A., Balko, Justin M., Beavis, Paul A., Darcy, Phillip K., Loi, Sherene
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605577/
https://ncbi.nlm.nih.gov/pubmed/28928458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00728-9
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