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Deacetylation of topoisomerase I is an important physiological function of E. coli CobB
Escherichia coli topoisomerase I (TopA), a regulator of global and local DNA supercoiling, is modified by N(ε)-Lysine acetylation. The NAD(+)-dependent protein deacetylase CobB can reverse both enzymatic and non-enzymatic lysine acetylation modification in E. coli. Here, we show that the absence of...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5605244/ https://ncbi.nlm.nih.gov/pubmed/28398568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx250 |
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