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Anti-Melanoma Activities of Haspin Inhibitor CHR-6494 Deployed as a Single Agent or in a Synergistic Combination with MEK Inhibitor

Background: Melanoma is a heterogeneous malignancy that presents an immense challenge in therapeutic development. Recent approaches targeting the oncogenic MAP kinase pathways have shown tremendous improvement in the overall survival of patients with advanced melanoma. However, there is still an urg...

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Vydáno v:J Cancer
Hlavní autoři: Han, Lili, Wang, Peiling, Sun, Yang, Liu, Sijing, Dai, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604444/
https://ncbi.nlm.nih.gov/pubmed/28928884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.20319
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