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Anti-Melanoma Activities of Haspin Inhibitor CHR-6494 Deployed as a Single Agent or in a Synergistic Combination with MEK Inhibitor

Background: Melanoma is a heterogeneous malignancy that presents an immense challenge in therapeutic development. Recent approaches targeting the oncogenic MAP kinase pathways have shown tremendous improvement in the overall survival of patients with advanced melanoma. However, there is still an urg...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Han, Lili, Wang, Peiling, Sun, Yang, Liu, Sijing, Dai, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604444/
https://ncbi.nlm.nih.gov/pubmed/28928884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.20319
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