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Illustrating, Quantifying, and Correcting for Bias in Post-hoc Analysis of Gene-Based Rare Variant Tests of Association

To date, gene-based rare variant testing approaches have focused on aggregating information across sets of variants to maximize statistical power in identifying genes showing significant association with diseases. Beyond identifying genes that are associated with diseases, the identification of caus...

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Bibliografski detalji
Izdano u:Front Genet
Glavni autori: Grinde, Kelsey E., Arbet, Jaron, Green, Alden, O'Connell, Michael, Valcarcel, Alessandra, Westra, Jason, Tintle, Nathan
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603735/
https://ncbi.nlm.nih.gov/pubmed/28959274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2017.00117
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