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A general approach for combining diverse rare variant association tests provides improved robustness across a wider range of genetic architectures

The widespread availability of genome sequencing data made possible by way of next-generation technologies has yielded a flood of different gene-based rare variant association tests. Most of these tests have been published because they have superior power for particular genetic architectures. Howeve...

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Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: Greco, Brian, Hainline, Allison, Arbet, Jaron, Grinde, Kelsey, Benitez, Alejandra, Tintle, Nathan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930097/
https://ncbi.nlm.nih.gov/pubmed/26508571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2015.194
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