Conjugation of wildtype and hypoallergenic mugwort allergen Art v 1 to flagellin induces IL-10-DC and suppresses allergen-specific TH2-responses in vivo

Allergies to weed pollen including members of the Compositae family, such as mugwort, ragweed, and feverfew are spreading worldwide. To efficiently treat these newly arising allergies, allergen specific immunotherapy needs to be improved. Therefore, we generated novel vaccine candidates consisting o...

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Foilsithe in:Sci Rep
Main Authors: Schülke, Stefan, Kuttich, Kirsten, Wolfheimer, Sonja, Duschek, Nadine, Wangorsch, Andrea, Reuter, Andreas, Briza, Peter, Pablos, Isabel, Gadermaier, Gabriele, Ferreira, Fatima, Vieths, Stefan, Toda, Masako, Scheurer, Stephan
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2017
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603567/
https://ncbi.nlm.nih.gov/pubmed/28924222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11972-w
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