Immunotherapy with Native Molecule rather than Hypoallergenic Variant of Pru p 3, the Major Peach Allergen, Shows Beneficial Effects in Mice

BACKGROUND: The use of hypoallergenic derivatives is considered beneficial to promote the safety and efficacy of allergen-specific immunotherapy. We aimed to assess the efficacy of reduced and alkylated (R/A) Pru p 3, a hypoallergenic folding variant of the major peach allergen, in subcutaneous immu...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Rodriguez, Maria J., Wangorsch, Andrea, Gomez, Francisca, Schülke, Stefan, Torres, Maria J., Vieths, Stefan, Scheurer, Stephan, Toda, Masako, Mayorga, Cristobalina
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020533/
https://ncbi.nlm.nih.gov/pubmed/30009186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3479185
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