Conjugation of wildtype and hypoallergenic mugwort allergen Art v 1 to flagellin induces IL-10-DC and suppresses allergen-specific TH2-responses in vivo

Allergies to weed pollen including members of the Compositae family, such as mugwort, ragweed, and feverfew are spreading worldwide. To efficiently treat these newly arising allergies, allergen specific immunotherapy needs to be improved. Therefore, we generated novel vaccine candidates consisting o...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Schülke, Stefan, Kuttich, Kirsten, Wolfheimer, Sonja, Duschek, Nadine, Wangorsch, Andrea, Reuter, Andreas, Briza, Peter, Pablos, Isabel, Gadermaier, Gabriele, Ferreira, Fatima, Vieths, Stefan, Toda, Masako, Scheurer, Stephan
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603567/
https://ncbi.nlm.nih.gov/pubmed/28924222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11972-w
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