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Constraints and consequences of the emergence of amino acid repeats in eukaryotic proteins
Proteins with amino acid homorepeats have the potential to be detrimental to cells and are often associated with human diseases. Why then are homorepeats prevalent in eukaryotic proteomes? In yeast, we find that homorepeats are enriched in proteins that are essential, pleiotropic and buffer environm...
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| Pubblicato in: | Nat Struct Mol Biol |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5603276/ https://ncbi.nlm.nih.gov/pubmed/28805808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3441 |
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