Variable Glutamine-Rich Repeats Modulate Transcription Factor Activity

Excessive expansions of glutamine (Q)-rich repeats in various human proteins are known to result in severe neurodegenerative disorders such as Huntington’s disease and several ataxias. However, the physiological role of these repeats and the consequences of more moderate repeat variation remain unkn...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Gemayel, Rita, Chavali, Sreenivas, Pougach, Ksenia, Legendre, Matthieu, Zhu, Bo, Boeynaems, Steven, van der Zande, Elisa, Gevaert, Kris, Rousseau, Frederic, Schymkowitz, Joost, Babu, M. Madan, Verstrepen, Kevin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543046/
https://ncbi.nlm.nih.gov/pubmed/26257283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.07.003
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