Variable Glutamine-Rich Repeats Modulate Transcription Factor Activity

Excessive expansions of glutamine (Q)-rich repeats in various human proteins are known to result in severe neurodegenerative disorders such as Huntington’s disease and several ataxias. However, the physiological role of these repeats and the consequences of more moderate repeat variation remain unkn...

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Pubblicato in:Mol Cell
Autori principali: Gemayel, Rita, Chavali, Sreenivas, Pougach, Ksenia, Legendre, Matthieu, Zhu, Bo, Boeynaems, Steven, van der Zande, Elisa, Gevaert, Kris, Rousseau, Frederic, Schymkowitz, Joost, Babu, M. Madan, Verstrepen, Kevin J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543046/
https://ncbi.nlm.nih.gov/pubmed/26257283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.07.003
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