Variable Glutamine-Rich Repeats Modulate Transcription Factor Activity

Excessive expansions of glutamine (Q)-rich repeats in various human proteins are known to result in severe neurodegenerative disorders such as Huntington’s disease and several ataxias. However, the physiological role of these repeats and the consequences of more moderate repeat variation remain unkn...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell
Prif Awduron: Gemayel, Rita, Chavali, Sreenivas, Pougach, Ksenia, Legendre, Matthieu, Zhu, Bo, Boeynaems, Steven, van der Zande, Elisa, Gevaert, Kris, Rousseau, Frederic, Schymkowitz, Joost, Babu, M. Madan, Verstrepen, Kevin J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cell Press 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543046/
https://ncbi.nlm.nih.gov/pubmed/26257283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.07.003
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