Candidate gene analysis for Alzheimer’s disease in adults with Down syndrome

Individuals with Down syndrome (DS) overexpress many genes on chromosome 21 due to trisomy and have high risk of dementia due to the Alzheimer’s disease (AD) neuropathology. However, there is a wide range of phenotypic differences (e.g., age at onset of AD, amyloid β levels) among adults with DS, su...

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Publicado en:Neurobiol Aging
Autores principales: Lee, Joseph H., Lee, Annie J., Dang, Lam-Ha, Pang, Deborah, Kisselev, Sergey, Krinsky-McHale, Sharon J., Zigman, Warren B., Luchsinger, José A., Silverman, Wayne, Tycko, Benjamin, Clark, Lorraine N., Schupf, Nicole
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603247/
https://ncbi.nlm.nih.gov/pubmed/28554490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.04.018
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