Candidate gene analysis for Alzheimer’s disease in adults with Down syndrome

Individuals with Down syndrome (DS) overexpress many genes on chromosome 21 due to trisomy and have high risk of dementia due to the Alzheimer’s disease (AD) neuropathology. However, there is a wide range of phenotypic differences (e.g., age at onset of AD, amyloid β levels) among adults with DS, su...

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Xehetasun bibliografikoak
Argitaratua izan da:Neurobiol Aging
Egile Nagusiak: Lee, Joseph H., Lee, Annie J., Dang, Lam-Ha, Pang, Deborah, Kisselev, Sergey, Krinsky-McHale, Sharon J., Zigman, Warren B., Luchsinger, José A., Silverman, Wayne, Tycko, Benjamin, Clark, Lorraine N., Schupf, Nicole
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603247/
https://ncbi.nlm.nih.gov/pubmed/28554490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.04.018
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