Candidate genes for Alzheimer’s disease are associated with individual differences in plasma levels of beta amyloid peptides in adults with Down syndrome

We examined the contribution of candidate genes for Alzheimer’s disease (AD) on Chromosome 21 and other chromosomes to differences in Aβ peptide levels in a cohort of adults with DS, a population at high risk for AD. Participants were 254 non-demented adults with Down syndrome, 30–78 years of age. G...

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發表在:Neurobiol Aging
Main Authors: Schupf, Nicole, Lee, Annie, Park, Naeun, Dang, Lam-Ha, Pang, Deborah, Yale, Alexander, Oh, David Kyung-Taek, Krinsky-McHale, Sharon J., Jenkins, Edmund C., Luchsinger, José A., Zigman, Warren B., Silverman, Wayne, Tycko, Benjamin, Kisselev, Sergey, Clark, Lorraine, Lee, Joseph H.
格式: Artigo
語言:Inglês
出版: 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562880/
https://ncbi.nlm.nih.gov/pubmed/26166206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.06.020
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