Candidate gene analysis for Alzheimer’s disease in adults with Down syndrome

Individuals with Down syndrome (DS) overexpress many genes on chromosome 21 due to trisomy and have high risk of dementia due to the Alzheimer’s disease (AD) neuropathology. However, there is a wide range of phenotypic differences (e.g., age at onset of AD, amyloid β levels) among adults with DS, su...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Lee, Joseph H., Lee, Annie J., Dang, Lam-Ha, Pang, Deborah, Kisselev, Sergey, Krinsky-McHale, Sharon J., Zigman, Warren B., Luchsinger, José A., Silverman, Wayne, Tycko, Benjamin, Clark, Lorraine N., Schupf, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603247/
https://ncbi.nlm.nih.gov/pubmed/28554490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.04.018
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados