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Loss of liver-specific and sexually dimorphic gene expression by aryl hydrocarbon receptor activation in C57BL/6 mice

The aryl hydrocarbon receptor (AhR) is a highly conserved transcription factor that mediates a broad spectrum of species-, strain-, sex-, age-, tissue-, and cell-specific responses elicited by structurally diverse ligands including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Dose-dependent effects o...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Nault, Rance, Fader, Kelly A., Harkema, Jack R., Zacharewski, Tim
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602546/
https://ncbi.nlm.nih.gov/pubmed/28922406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184842
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