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Neuropilin-1 promotes Hedgehog signaling through a novel cytoplasmic motif

Hedgehog (HH) signaling critically regulates embryonic and postnatal development as well as adult tissue homeostasis, and its perturbation can lead to developmental disorders, birth defects, and cancers. Neuropilins (NRPs), which have well-defined roles in Semaphorin and VEGF signaling, positively r...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Pinskey, Justine M., Franks, Nicole E., McMellen, Alexandra N., Giger, Roman J., Allen, Benjamin L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602381/
https://ncbi.nlm.nih.gov/pubmed/28667171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.783845
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