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Neuropilin-1 promotes Hedgehog signaling through a novel cytoplasmic motif

Hedgehog (HH) signaling critically regulates embryonic and postnatal development as well as adult tissue homeostasis, and its perturbation can lead to developmental disorders, birth defects, and cancers. Neuropilins (NRPs), which have well-defined roles in Semaphorin and VEGF signaling, positively r...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Pinskey, Justine M., Franks, Nicole E., McMellen, Alexandra N., Giger, Roman J., Allen, Benjamin L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602381/
https://ncbi.nlm.nih.gov/pubmed/28667171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.783845
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