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Spinocerebellar Ataxia Type 2: Clinicogenetic Aspects, Mechanistic Insights, and Management Approaches

Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant cerebellar ataxia that occurs as a consequence of abnormal CAG expansions in the ATXN2 gene. Progressive clinical features result from the neurodegeneration of cerebellum and extra-cerebellar structures including the pons, the basal gangl...

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Bibliografski detalji
Izdano u:Front Neurol
Glavni autori: Velázquez-Pérez, Luis C., Rodríguez-Labrada, Roberto, Fernandez-Ruiz, Juan
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601978/
https://ncbi.nlm.nih.gov/pubmed/28955296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2017.00472
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