Potential independent action of sigma receptor ligands through inhibition of the Kv2.1 channel

The sigma-1 receptor (σ1-R) and sigma-2 receptor (σ2-R) are potential drug targets for treatment of cancer, pain, depression, retinal degeneration and other neuronal diseases. Previous reports show that sigma-1 receptor modulates the activities of multiple channels. We are interested in possible sig...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Liu, Xinying, Fu, Yingmei, Yang, Huan, Mavlyutov, Timur, Li, Jun, McCurdy, Christopher R., Guo, Lian-Wang, Pattnaik, Bikash R.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601737/
https://ncbi.nlm.nih.gov/pubmed/28938641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19581
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