3-Decylcatechol induces autophagy-mediated cell death through the IRE1α/JNK/p62 in hepatocellular carcinoma cells

The natural, phenolic lipid urushiol exhibits both antioxidant and anticancer activities; however, its biological activity on hepatocellular carcinoma (HCC) has not been previously investigated. Here, we demonstrate that an urushiol derivative, 3-decylcatechol (DC), induces human HCC Huh7 cell death...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Go, Da-Hye, Lee, Yu Geon, Lee, Da-Hye, Kim, Jin-A, Jo, In-Hwa, Han, Yeon Soo, Jo, Yong Hun, Kim, Kwang-Youn, Seo, Young-Kyo, Moon, Jae-Hak, Jung, Chang Hwa, Jeon, Tae-Il
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601693/
https://ncbi.nlm.nih.gov/pubmed/28938597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17732
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