L-Ascorbic Acid Inhibits Breast Cancer Growth by Inducing IRE/JNK/CHOP-Related Endoplasmic Reticulum Stress-Mediated p62/SQSTM1 Accumulation in the Nucleus

Anticancer effects of L-ascorbic acid (Vitamin C, L-AA) have been reported in various types of cancers. L-AA intake reduces breast cancer recurrence and mortality; however, the role of L-AA in the treatment of breast cancer remains poorly understood. In this study, we investigated the effect and mec...

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Publicat a:Nutrients
Autors principals: Choi, Youn Kyung, Kang, Jung-Il, Han, Sanghoon, Kim, Young Ree, Jo, Jaemin, Kang, Yong Woo, Choo, Do Ryeon, Hyun, Jin Won, Koh, Young Sang, Yoo, Eun-Sook, Kang, Hee-Kyoung
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7284633/
https://ncbi.nlm.nih.gov/pubmed/32397306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu12051351
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