Endoplasmic Reticulum Stress Is Involved in Stress-Induced Hypothalamic Neuronal Injury in Rats via the PERK-ATF4-CHOP and IRE1-ASK1-JNK Pathways

OBJECTIVE: As a high-level nerve center that regulates visceral and endocrine activity, the hypothalamus plays an important role in regulating the body’s stress response. Previous studies have shown that stress can cause damage to hypothalamic neurons. The present study aimed to further clarify the...

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Udgivet i:Front Cell Neurosci
Main Authors: Yi, Shanyong, Chen, Ke, Zhang, Lihua, Shi, Weibo, Zhang, Yaxing, Niu, Shiba, Jia, Miaomiao, Cong, Bin, Li, Yingmin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509942/
https://ncbi.nlm.nih.gov/pubmed/31130849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00190
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