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Endoplasmic Reticulum Stress Is Involved in Stress-Induced Hypothalamic Neuronal Injury in Rats via the PERK-ATF4-CHOP and IRE1-ASK1-JNK Pathways

OBJECTIVE: As a high-level nerve center that regulates visceral and endocrine activity, the hypothalamus plays an important role in regulating the body’s stress response. Previous studies have shown that stress can cause damage to hypothalamic neurons. The present study aimed to further clarify the...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Yi, Shanyong, Chen, Ke, Zhang, Lihua, Shi, Weibo, Zhang, Yaxing, Niu, Shiba, Jia, Miaomiao, Cong, Bin, Li, Yingmin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509942/
https://ncbi.nlm.nih.gov/pubmed/31130849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00190
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