Chimeric Antigen Receptor-Redirected Regulatory T Cells Suppress Experimental Allergic Airway Inflammation, a Model of Asthma

Cellular therapy with chimeric antigen receptor (CAR)-redirected cytotoxic T cells has shown impressive efficacy in the treatment of hematologic malignancies. We explored a regulatory T cell (Treg)-based therapy in the treatment of allergic airway inflammation, a model for asthma, which is character...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Skuljec, Jelena, Chmielewski, Markus, Happle, Christine, Habener, Anika, Busse, Mandy, Abken, Hinrich, Hansen, Gesine
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600908/
https://ncbi.nlm.nih.gov/pubmed/28955341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01125
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