IL-27 Is Essential for Suppression of Experimental Allergic Asthma by the TLR7/8 Agonist R848 (Resiquimod)

Different models of experimental allergic asthma have shown that the TLR7/8 agonist resiquimod (R848) is a potential inhibitor of type 2 helper cell–driven inflammatory responses. However, the mechanisms mediating its therapeutic effects are not fully understood. Using a model of experimental allerg...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Jirmo, Adan Chari, Daluege, Kathleen, Happle, Christine, Albrecht, Melanie, Dittrich, Anna-Maria, Busse, Mandy, Habener, Anika, Skuljec, Jelena, Hansen, Gesine
Format: Artigo
Sprog:Inglês
Udgivet: AAI 2016
Fag:
Allergy and Other Hypersensitivities
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114883/
https://ncbi.nlm.nih.gov/pubmed/27799314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601094
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