DNA-methyltransferase 1 Induces Dedifferentiation of Pancreatic Cancer Cells through Silencing of Krüppel-like factor 4 Expression

OBJECTIVE: The dismal prognosis of pancreatic cancer has been linked to poor tumor differentiation. However, molecular basis of pancreatic cancer differentiation and potential therapeutic value of the underlying molecules remain unknown. We investigated the mechanistic underexpression of Krüppel-lik...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Xie, Victoria K, Li, Zhiwei, Yan, Yongmin, Jia, Zhiliang, Zuo, Xiangsheng, Ju, Zhenlin, Wang, Jing, Du, Jiawei, Xie, Dacheng, Xie, Keping, Wei, Daoyan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600846/
https://ncbi.nlm.nih.gov/pubmed/28659310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-0387
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