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Disordered N–Terminal Domain of Human Uracil DNA Glycosylase (hUNG2) Enhances DNA Translocation
Nuclear human uracil–DNA glycosylase (hUNG2) initiates base excision repair (BER) of genomic uracils generated through misincorporation of dUMP or through deamination of cytosines. Like many human DNA glycosylases, hUNG2 contains an unstructured N–terminal domain that encodes a nuclear localization...
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| Publicado no: | ACS Chem Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5600714/ https://ncbi.nlm.nih.gov/pubmed/28787572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00521 |
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