Disordered N–Terminal Domain of Human Uracil DNA Glycosylase (hUNG2) Enhances DNA Translocation

Nuclear human uracil–DNA glycosylase (hUNG2) initiates base excision repair (BER) of genomic uracils generated through misincorporation of dUMP or through deamination of cytosines. Like many human DNA glycosylases, hUNG2 contains an unstructured N–terminal domain that encodes a nuclear localization...

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Detaylı Bibliyografya
Yayımlandı:ACS Chem Biol
Asıl Yazarlar: Rodriguez, Gaddiel, Esadze, Alexandre, Weiser, Brian P., Schonhoft, Joseph D., Cole, Philip A., Stivers, James T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600714/
https://ncbi.nlm.nih.gov/pubmed/28787572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00521
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