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Measurement of nanoscale DNA translocation by uracil DNA glycosylase in human cells
DNA ‘sliding’ by human repair enzymes is considered to be important for DNA damage detection. Here, we transfected uracil-containing DNA duplexes into human cells and measured the probability that nuclear human uracil DNA glycosylase (hUNG2) excised two uracil lesions spaced 10–80 bp apart in a sing...
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| Publicado en: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5716149/ https://ncbi.nlm.nih.gov/pubmed/29036472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx848 |
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