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Synthesis and Evaluation of Agelastatin Derivatives as Potent Modulators for Cancer Invasion and Metastasis

The synthesis of new agelastatin alkaloid derivatives and their anticancer evaluation in the context of the breast cancer microenvironment is described. A variety of N1-alkyl and C5-ether agelastatin derivatives were accessed via application of our strategy for convergent imidazolone synthesis from...

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Bibliografski detalji
Izdano u:J Org Chem
Glavni autori: Antropow, Alyssa H., Xu, Kun, Buchsbaum, Rachel J., Movassaghi, Mohammad
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600481/
https://ncbi.nlm.nih.gov/pubmed/28696693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b01162
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