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Synthesis and Anticancer Activity of all known (−)-Agelastatin Alkaloids

The full details for our enantioselective total syntheses of (−)-agelastatins A–F (1–6), the evolution of a new methodology for synthesis of substituted azaheterocycles, and the first side-by-side evaluation of all known (−)-agelastatin alkaloids against nine human cancer cell lines are described. O...

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Detalhes bibliográficos
Main Authors: Han, Sunkyu, Siegel, Dustin S., Morrison, Karen C., Hergenrother, Paul J., Movassaghi, Mohammad
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920459/
https://ncbi.nlm.nih.gov/pubmed/24152243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo4020112
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