The fibroblast Tiam1-osteopontin pathway modulates breast cancer invasion and metastasis

BACKGROUND: The tumor microenvironment has complex effects in cancer pathophysiology that are not fully understood. Most cancer therapies are directed against malignant cells specifically, leaving pro-malignant signals from the microenvironment unaddressed. Defining specific mechanisms by which the...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Breast Cancer Res
Main Authors: Xu, Kun, Tian, Xuejun, Oh, Sun Y., Movassaghi, Mohammad, Naber, Stephen P., Kuperwasser, Charlotte, Buchsbaum, Rachel J.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730665/
https://ncbi.nlm.nih.gov/pubmed/26821678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0674-8
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