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Tiam1-regulated osteopontin in senescent fibroblasts contributes to the migration and invasion of associated epithelial cells

The tumor microenvironment undergoes changes concurrent with neoplastic progression. Cancer incidence increases with aging and is associated with tissue accumulation of senescent cells. Senescent fibroblasts are thought to contribute to tumor development in aging tissues. We have shown that fibrobla...

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Bibliografiset tiedot
Päätekijät: Liu, Jiewei, Xu, Kun, Chase, Maya, Ji, Yuxin, Logan, Jennifer K., Buchsbaum, Rachel J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Company of Biologists 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283874/
https://ncbi.nlm.nih.gov/pubmed/22302986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.089466
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