The inhibitors of cyclin-dependent kinases and GSK-3β enhance osteoclastogenesis

Osteoclasts are multinucleated cells with bone resorption activity that is crucial for bone remodeling. RANK‐RANKL (receptor activator of nuclear factor κB ligand) signaling has been shown as a main signal pathway for osteoclast differentiation. However, the molecular mechanism and the factors regul...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Akiba, Yosuke, Mizuta, Akiko, Kakihara, Yoshito, Nakata, Juri, Nihara, Jun, Saito, Isao, Egusa, Hiroshi, Saeki, Makio
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600418/
https://ncbi.nlm.nih.gov/pubmed/28955831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.12.011
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