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The inhibitors of cyclin-dependent kinases and GSK-3β enhance osteoclastogenesis
Osteoclasts are multinucleated cells with bone resorption activity that is crucial for bone remodeling. RANK‐RANKL (receptor activator of nuclear factor κB ligand) signaling has been shown as a main signal pathway for osteoclast differentiation. However, the molecular mechanism and the factors regul...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2016-03-01
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Colecção: | Biochemistry and Biophysics Reports |
Assuntos: | |
Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2405580815001569 |
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