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The inhibitors of cyclin-dependent kinases and GSK-3β enhance osteoclastogenesis

Osteoclasts are multinucleated cells with bone resorption activity that is crucial for bone remodeling. RANK‐RANKL (receptor activator of nuclear factor κB ligand) signaling has been shown as a main signal pathway for osteoclast differentiation. However, the molecular mechanism and the factors regul...

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Detalhes bibliográficos
Main Authors: Yosuke Akiba, Akiko Mizuta, Yoshito Kakihara, Juri Nakata, Jun Nihara, Isao Saito, Hiroshi Egusa, Makio Saeki
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016-03-01
Colecção:Biochemistry and Biophysics Reports
Assuntos:
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2405580815001569
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